Category: Harm Reduction

  • Exposing Claptrap

    Exposing Claptrap

    Photo: Myriam Zilles | PixaBay

    If England wants to achieve its target of reducing smoking incidence to 5 percent by 2030, it should debunk the myriad stories that are presenting vaping in an inaccurately negative light.

    By George Gay

    One figure in a recent report on smoking habits in the U.K. seemed to be of special note. According to the report, “Adult smoking habits in the U.K.: 2019”*, which was published on July 7 by the Office for National Statistics (ONS), 52.7 percent of Great Britain’s smokers say they intend (my emphasis) to quit smoking.

    Only 52.7 percent? That is below the figures usually quoted in respect of the proportion of smokers who want to quit. For instance, according to the September 2018 edition of Public Health England’s (PHE) Health Matters, about 60 percent of England’s smokers wanted (my emphasis) to quit.

    So these figures raise an interesting issue, assuming the numbers are correct and are reasonably comparable*. For one thing, it seems odd that something of the order of 7.3 percent of smokers want to give up but don’t intend to do so because that means more than half a million people are seemingly acting irrationally, even looked at from their own subjective point of view. I mean, if our actions are observed by others, we are probably all seen to be acting irrationally at one time or another, but it is quite another matter for an individual to knowingly act in what she regards to be an irrational manner.

    There could, however, be another explanation for this phenomenon. It could be that roughly half a million smokers in Great Britain have decided that while they want to quit, they are so sure they cannot that they don’t intend to try. If these people are fatalist or determinists, so be it. But it is a different matter if they have been convinced that they cannot quit. And this could be the case. Some of those in tobacco control have seemingly done what they would consider to be an excellent job of convincing smokers that quitting is almost impossible.

    But this, of course, is nonsense. The ONS report also says that “62.5 percent of those who have ever smoked [in Great Britain] said they had quit, based on our estimates from the Opinions and Lifestyle Survey.” Interestingly, the ONS report presents, too, a comparison with the equivalent figure for 1974, 26.7 percent, which perhaps casts doubt on the claim that manufacturers in recent years have rigged formulations to make cigarettes more addictive—whatever more addictive might mean.

    In fact, you would have to doubt whether the 52.7 percent figure is meaningful. The report also says that 21.2 percent of smokers intend to quit within the next three months, so it has to be assumed the other 31.5 percent have put no time limit on their intentions. In this case, I would suggest that while the “intention” expressed by the 21.2 percent of smokers is akin to a student’s multi-colored study plan, the “intention” expressed by the 31.5 percent of smokers who are looking beyond three months is nothing more than a pipe dream.

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    Why it matters

    This is important for the authorities because England has a target of reducing its incidence of smoking to 5 percent or lower by 2030. As of last year, the ONS reports, the incidence was down to 13.9 percent, so if the proportion of smokers in England falls during the next 11 years by the same amount as it fell between 2018 and 2019 in Great Britain (14.7 percent to 14.1 percent), the target is not going to be met.

    The question is: Will the incidence fall by 0.6 of a percentage point year-on-year? In which case, it would drop to 7 percent to 8 percent by 2030. The ONS researchers referred to the 0.6 percentage point fall between 2018 and 2019 as “significant,” so it could be difficult to maintain such a fall every year given that it is probably reasonable to assume that the further the overall percentage falls, the more the smoker base will be reduced to a hard core. On the other hand, the further the overall percentage falls, the smaller the community of smokers will become, which raises the question of how long even committed smokers will continue with their habit once most of their acquaintances no longer join them outside the pub for a smoke.

    And, of course, there is the million-dollar question around what effect the spread of Covid-19 has had and is having on the incidence of smoking. How many smokers are going to believe those who suggest that smoking and/or consuming tobacco or nicotine can help prevent the onset of the disease, and how many are going to worry that, as some claim, smoking and/or the consumption of tobacco or nicotine is likely to make their health outcomes worse if they do contract the disease?

    But there is a billion-dollar question too. Are those intent on stopping smokers quitting their habit by switching to less risky tobacco or nicotine products going to continue to enjoy “success”? It has been said many times that the switch to vaping has stalled in the U.K., something that is strange because public health in the country has generally acted in a reasonably supportive way when it comes to vaping and its benefits. For instance, take this passage from Health Matters:

    “There is a widespread misconception amongst smokers and health professionals that most of the harm of smoking comes from nicotine. This is perhaps the greatest obstacle we face as it leads to both nicotine-replacement therapy (NRT) and e-cigarettes being perceived as harmful, and as a result, smokers may not make a quit attempt using one of these routes.

    Leading health organizations, including the Royal College of Physicians, Royal College of General Practitioners and the British Medical Association have all provided advice on the important role of e-cigarettes in helping smokers to quit.”

    One of the issues that holds smokers back from switching to vaping is that smokers enjoy smoking and will clutch at any straws that help them, in good conscience, to continue with their habit, so if somebody comes along and casts doubt on the safety of consuming nicotine by other means, they will latch on to that doubt, no matter how ludicrous the ideas on which that doubt is based are. As is described in the accompanying piece, even though the lung injury saga of 2019 played out in the U.S. and involved a substance not permitted for vaping in the U.K., it probably damaged the cause of vaping in the U.K.

    And there is no end to such tales. One story precis I saw recently claimed in its first sentence that “New research … shows that there are more unknown dangers associated with vaping.” What is written here makes no sense. More than what? And how do we who are not Donald Rumsfeld know that there are unknown dangers? In addition, the research seemed to assume that flavor molecules that attacked plastic would have the same effect on human tissue—somewhat akin to assuming that your stomach lining ends up looking like the inside of a teapot.

    I cannot help thinking that if progress is to be made in reducing the U.K.’s smoking incidence in line with its 2030 target, organizations such as PHE should, as well as continuing their helpful work in trying to publicize the positive aspects of vaping, act quickly to debunk in the public sphere the myriad stories that are presenting vaping in an inaccurately negative light.

    *The report’s figures come from two separate data sources, with those for the U.K. (England, Wales, Scotland and Northern Ireland) coming from the Annual Population Survey and those for Great Britain (England, Wales and Scotland) coming from the Opinion and Lifestyle Survey. I have taken the liberty of conflating some data in respect of Great Britain and England, and I have also conflated data that refers to adult smokers as being over the age of 16 and data referring to adult smokers as over 18. I have done this because it is the concepts behind the figures rather than the figures themselves that are of interest here.

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    Philip Morris’ progress toward a smoke-free England

    Picture of Patrick Muttart
    Patrick Muttart

    It is now about three years since Philip Morris posed the question, Can Britain go smoke-free in the next 10 years? and Tobacco Reporter in July took the opportunity of this anniversary to ask Patrick Muttart, director of external affairs for the U.K. and Ireland at Philip Morris Limited, what progress had been made.

    Tobacco Reporter: Part of the problem that Britain faced three years ago was that while vaping had helped a lot of people quit smoking, the switch from smoking to vaping had, for a number of reasons, stalled. Assuming that there has been some uptick in switching from smoking to the consumption of less-risky products, which products have been responsible for that uptick?

    Philip Morris U.K.: Smoking prevalence rates are falling in the U.K. as more people either quit cigarettes altogether or switch to alternative products. Official figures from the ONS [Office for National Statistics] in July show that the proportion of current smokers in the U.K. has dropped from 14.7 percent in 2018 to 14.1 percent in 2019—continuing a downward trend since 2011. Central to this decline has been the role of smoke-free alternatives, such as e-cigarettes and heated-tobacco and more recently nicotine pouches.

    In Great Britain, nearly 3 million people use an e-cigarette. Despite this, regular e-cigarette use has plateaued in recent years. A growing number of smokers in the U.K. mistakenly believe that vaping is equally or more harmful than smoking following the highly publicized reports in the U.S. of the lung injury outbreak in 2019. The substance identified as the primary cause of the outbreak in the U.S. is banned in regulated vaping products in the U.K. Nevertheless, these false fears have clearly affected smokers’ views towards vaping in the U.K. and come as the number of smokers who intend to quit continues to fall.

    With product development and scientific substantiation working in lockstep together, tobacco manufacturers must therefore offer smoke-free alternatives that adult smokers can have confidence in. This will go some way in easing safety concerns, so smokers aren’t deterred from switching if they cannot quit altogether.

    Philip Morris has invested significantly in its smokefree portfolio to offer products that are a better alternative to smoking and meet adult consumer preferences. IQOS, a heated-tobacco product, produces up to 95 percent less harmful chemicals* compared to cigarettes and by using real tobacco instead of liquid, delivers a more familiar and satisfying tobacco experience.

    In the U.K., heated-tobacco volumes during the second quarter of 2020 increased more than five-fold over the prior year quarter, demonstrating the growing popularity in the category while underlining the huge role that tobacco-based smoke-free products can play in helping people switch to less harmful alternatives.

    Do you think the U.S. Food and Drug Administration’s (FDA) authorization of the marketing in the U.S. of IQOS as a modified-risk tobacco product (MRTP) will help progress toward your smoke-free target in the U.K.?

    The FDA’s authorization of the marketing of IQOS in the U.S. is an important milestone on our journey to becoming smoke-free. It marks the first time that [the] FDA has granted MRTP marketing orders for an innovative electronic alternative to cigarettes.

    Following a multi-year review of PMI’s [Philip Morris International’s] evidence as well as a number of independent studies, the FDA decided that smokers who switch completely from conventional cigarettes to IQOS significantly reduce their exposure to harmful or potentially harmful chemicals in accordance with their interpretation of the U.S. law. Their authorization confirms that IQOS is distinctly different to cigarettes because it has been demonstrated to reduce exposure to harmful chemicals and that this information should be communicated to consumers to help guide their choice.

    While the MRTP designation applies in the U.S., it is consistent with earlier conclusions of other leading regulatory and scientific bodies, including those in the U.K., which found that IQOS emits lower levels of harmful toxicants.

    We believe that this latest decision by the FDA—and its previous decision to grant an oral tobacco alternative a modified-risk status—strengthens the argument for the U.K. to carefully review these next-generation tobacco-based alternatives, which have undergone comprehensive and robust scientific assessment. —G.G.

    *Philip Morris points out that this does not necessarily equal a 95 percent reduction in risk. IQOS is not risk free.

  • Call for Common Ground in THR

    Call for Common Ground in THR

    Joe Murillo

    For tobacco harm reduction to be successful, it is imperative that alternative products can compete with combustible cigarettes and that adult smokers have clear information on a product’s relative risk compared to smoking, according to Juul Labs Chief Regulatory Officer Joe Murillo.
     
    In his closing remarks at the 2020 Global Tobacco & Nicotine Forum (GTNF), Murillo spoke on how the category can sustainably accelerate the market away from combustible products while at the same time combating underage use and fostering a more responsible marketplace for vapor products that ensures equal access for all adult smokers.
     
    Murillo’s address pinpointed critical areas where the industry and stakeholders can find common ground in the pursuit of progress, including educating society on the benefits of tobacco harm reduction and using risk-proportionate regulation to elevate alternatives that can ultimately end the death and disease caused by smoking combustible cigarettes.
     
    According to Juul Labs, this year’s GTNF provided an invaluable opportunity for a diverse set of stakeholders to come together and speak about using innovation and regulation to create sustainable change in the tobacco and nicotine market.

  • 22nd Century Anticipates MRTP

    22nd Century Anticipates MRTP

    Photo: Myriam Zilles from Pixabay

    22nd Century Group plans to commercialize its VLN cigarette plan within 90 days of receiving a modified-risk tobacco product (MRTP) application.

    In a letter to shareholders, group CEO James A. Mish expressed optimism that the company’s VLN brand, which contains 95 percent less nicotine than other leading cigarette brands, would be granted MRTP status by the U.S. Food and Drug Administration (FDA).

    In March 2018, the FDA issued “Tobacco Product Standard for Nicotine Level of Combusted Cigarettes,” an advance notice of proposed rulemaking seeking public comment for consideration in developing a potential nicotine product standard.

    “We now believe it is not a matter of if but when our application will be granted, and we believe we are months, not years, away from securing our MRTP designation,” wrote Mish.

    Mish suggested that an MRTP would greatly boost 22nd Century’s market value.

    “Having the only combustible cigarette with a modified exposure claim authorized by the FDA […], could serve as a catalyst for 22nd Century’s commercial sales as even achieving just one-quarter of 1 percent—0.25 percent—market share of the U.S. tobacco market could result in revenues that may over time, based on current market multiples, drive the company’s market capitalization more than five to 10 times higher than it is today,” he said.

    “In addition, FDA authorizing the marketing of 22nd Century’s modified risk tobacco products with modified exposure claims would open multiple licensing opportunities for 22nd Century’s proprietary reduced nicotine content tobacco to accelerate the commercial and public health potential.”

  • BAT Calls for “Whole Society” Approach to Policymaking

    BAT Calls for “Whole Society” Approach to Policymaking

    Kingsley Wheaton (Photo: BAT)

    British American Tobacco’s (BAT) Chief Marketing Officer Kingsley Wheaton called for meaningful change in the way that global tobacco and nicotine policies are developed. He stressed the need for a United Nations-style “whole of society” approach to policy development and emphasized the benefits that this more stakeholder-inclusive tobacco harm reduction approach could deliver.

    Speaking at the first virtual GTNF, Wheaton also outlined the progress that BAT is making in transforming its business and pursuing its purpose to build “A Better Tomorrow.” He emphasized how a focus on innovation, transformation and sustainability is helping to accelerate change.

    Highlighting the positive role that the industry’s expertise and science can and should play, Wheaton set out a five-point framework to accelerate progress toward more effective tobacco harm reduction policies, including: an evidence-based approach, allowing robust science to lead to greater consumer choice, quality and confidence; proportionate regulation where science-based relative risk is understood and differentiated to guide regulatory policy; freedom to innovate to ensure products can evolve to meet changing consumer preferences; engagement, dialogue and communication to ensure regulators and consumers can make well-informed decisions; and responsible marketing freedoms that facilitate the acceleration of movement of consumers from combustible to noncombustible products.

     “At BAT, consumer-led innovation and product science are central to achieving our ‘A Better Tomorrow’ purpose,” says Wheaton. “We aim to reduce the health impact of our business through offering a greater choice of less-risky products to our consumers. We believe that a multi-category approach that includes e-cigarettes, tobacco-heated products and modern oral nicotine pouches is the most effective way to appeal to the diverse preferences of adult consumers around the world.

     “However, the key to accelerating the movement of smokers to less-risky alternatives cannot be solved by our industry alone. We need a seat at the harm reduction table to discuss these issues directly and openly with all stakeholders—including regulators and public health professionals alike. Only through collaborative efforts can we develop effective regulatory solutions that will enable real choice for consumers whilst still serving tobacco-related public health objectives.”

  • ‘Insufficient Progress on Harm Reduction’

    ‘Insufficient Progress on Harm Reduction’

    Most of the 15 largest tobacco companies are not making substantial progress in advancing harm reduction, according to The Foundation for a Smoke-Free World (FSFW).

    According to the foundation’s first Tobacco Transformation Index, some companies have made public commitments—backed by significant investments—to harm reduction, but many companies have not made these commitments. Committing to and implementing harm reduction and cessation strategies could help reduce tobacco-related deaths in the next two decades, according to the FSFW.

    “The Tobacco Transformation Index is the first index to rank the world’s largest 15 tobacco companies on their relative performance, commitment and transparency to deliver material progress in supporting tobacco harm reduction,” according to a press release. The index assesses the companies’ strategy and management, product sales, capital allocation, product offer, marketing, and lobbying and advocacy from 2017 to 2019.

    Swedish Match is ranked in first position. Philip Morris International, British American Tobacco, Altria, Imperial Brands, Japan Tobacco, KT&G, ITC Ltd., Swisher International, Tobacco Authority of Thailand, Vietnam National Tobacco, Gudang Garam, Djarum, Eastern Co. and China National Tobacco Corp. follow Swedish Match in the overall rankings.

  • Patents Granted for Sting-Free Snus

    Patents Granted for Sting-Free Snus

    Photo: Tobacco Reporter archive

    The U.S. Patent Office has granted Sting Free AB a patent (US 15/255,163) for a technology that makes snus and other nicotine pouch products more accessible to adult consumers by eliminating the stinging sensation associated with their use.

    The European Patent Organization too intends to grant a patent covering 39 nations for the technology. Sting Free AB already holds the Swedish patent rights to this invention.

    The new technology, which was first covered by Tobacco Reporter in July 2017, comprises a pouch of which one side is impermeable to liquids. In addition to eliminating the stinging sensation commonly associated with many pouch products, the technology also allows manufacturers to enhance flavors, pH levels and nicotine release profiles. Products that can benefit from its technology include snus, moist snuff, tobacco-free nicotine pouches and CBD, according to Sting Free AB.

    Snus is considered less risky to health than smoking, and many tobacco users, particularly in Sweden, have used the product to reduce or eliminate their exposure to the harmful byproducts of combustion.

    Grand View Research expects smokeless tobacco products to generate $5.6 billion globally in 2020 and $22.2 billion by 2025. Because the stinging sensation is often cited as the No. 1 deterrent for new users of oral nicotine products, Sting Free AB believes its new technology could expand the addressable market of adult consumers considerably.

    Bengt Wiberg

    “We foresee that the already impressive market growth for pouched products containing nicotine will increase substantially when more manufacturers and brands adopt our sting free technology,” says Sting Free AB CEO Bengt Wiberg.

    The sting-free technology has already been successfully produced in a prototype series using unmodified industrial snus packaging machines. In 2017, the innovation received a Golden Leaf Award in the “Most exciting newcomer to the industry” category at the GTNF in New York City.

    Sting Free AB has a nonexclusive licensing agreement with Swedish Match, the world’s largest Swedish snus manufacturer and producer of the successful Zyn nicotine pouch. It has also signed pre-licensing agreements with several other manufacturers of snus and nicotine pouch products.

  • Australia Rejects Tobacco Heating Products

    Australia Rejects Tobacco Heating Products

    Photo: Tobacco Reporter archive

    The Therapeutic Goods Administration (TGA) in Australia rejected an application from Philip Morris (PM) that would have allowed the sale of heated-tobacco products.
     
    This follows the Australian government’s ban on the import of nicotine-based e-cigarettes. Health Minister Greg Hunt planned to implement the ban beginning July 1 of this year, but the ban has now been pushed back to the beginning of 2021 to allow those who have been using e-cigarettes with nicotine to quit smoking combustibles to get prescriptions and end their addiction.
     
    The ban would make the import of vaporizer nicotine and e-cigarettes allowable only with a doctor’s prescription.
     
    There were 82 submissions in the TGA decision that supported heated-tobacco products, and the U.S. Food and Drug Administration concluded that PM’s tobacco-heating product “is expected to benefit the health of the population as a whole.” The TGA received submissions from the Lung Foundation, Cancer Council Australia, Australian Council on Health and Smoking, and the National Heart Foundation, though, that stated their concerns regarding public health risks of heated-tobacco products. The TGA ultimately decided there were “significant safety concerns with heated-tobacco products,” according to news.com.au.
     
    “Study after study shows that scientifically substantiated smoke-free products that do not generate smoke, while not risk-free, are a much better alternative for adult smokers who would otherwise continue to smoke cigarettes,” said Tammy Chan, Philip Morris managing director. “It’s time Australian authorities recognize that many adult smokers will continue to smoke cigarettes—the most harmful way of consuming nicotine—unless the government rethinks its tobacco control policy. Smoke-free products can play a role in reducing smoking rates.”
     
    According to Chan, Australia’s stance on smoke-free products is at odds with other countries; heated-tobacco products are available in 50 other countries.

  • No Baggage

    No Baggage

    Photo: Swedish Match

    Unburdened by the legacy of traditional tobacco products, nicotine pouches are starting to catch on in a variety of markets.

    By George Gay

    Having been asked to look into whether interest in and sales of nicotine pouches have increased in the wake of the Covid-19 pandemic, I have to own up to failure. In my own defense, however, I would suggest that the consumer buzz around these novel products had been getting louder from well before the onset of the virus and that any additional interest caused by the pandemic would probably have been difficult to discern against that background noise.

    Having said that, I did find some evidence of increased interest in nicotine pouches brought on, at least in part, by the pandemic. Jason Carignan, president of Dryft Sciences, which offers its Dryft brand of nicotine pouches in the U.S., made some interesting observations about the way that nicotine users had been reacting in the face of Covid-19 and how they might respond in the future. “Consumers are responding well to Dryft’s convenience, simplicity and functionality at a time when wearing masks is more prevalent and remaining indoors is required,” he said as part of a statement issued in response to a number of questions posed by TR. “Online subscriptions are increasingly attractive with deliver-by-mail options, and we’re receiving positive feedback about our different flavors and strengths, as well.

    “We are seeing new consumers arrive at Dryft with a desire to choose nicotine without toxins that accompany combustion—yes, that is true. But those consumers are also rethinking how nicotine is viewed in public health circles. They’re seeking fact-based discussion and research. They expect us to be responsive to their feedback. And they want the freedom to responsibly choose from alternatives in a future state that presents completely new nicotine products.”

    The Dryft nicotine pouch has been well-received in the marketplace, according to its manufacturer. (Photo: Dryft Sciences)

    Don’t inhale

    Aside from these remarks, I think there is a robust, common-sense argument to be made for why interest in nicotine pouches might have increased since the start of the pandemic. The initial information made public about Covid-19 concentrated on how the disease attacked the lungs, and so it wouldn’t have been unreasonable for cigarette smokers to have been concerned that their habit might exacerbate the damage done to their health should they contract Covid-19; this might well have led them to cast about for a form of tobacco/nicotine consumption that did not pose the same level of risk as smoking does.

    So where would they have headed? Well, I think that most reasonable people would conclude that vaping is hugely less risky than smoking is, but one of the current stumbling blocks here is that vaping too involves inhalation, albeit that in this case the inhalation avoids the toxic products of pyrolysis consumed in smoking. Add to this the fact that most smokers have been exposed to a cacophony of anti-vaping propaganda put out in many cases by people who should know better, and it is probably the case that smokers would look elsewhere for relief during the Covid-19 pandemic.

    And what better product than a no-burn, no-inhalation one whose low-risk credentials are backed by a comprehensive body of evidence stretching back decades? The problem here, however, is that snus, for all its advantages, comes with baggage acquired over its long history. It is beset by a back catalogue of negative health-risk reports that, while they might have been disproven, continue to weigh it down and hold it back.

    Which brings the smoker to nicotine pouches. These oral products, which contain no tobacco, are new enough not to carry such health-risk baggage and, indeed, it is difficult—but, alas, not impossible—to see where even those with an obsessive interest in stopping people enjoying tobacco or nicotine products could find fault. For instance, Swedish Match’s popular Zyn brand comprises only pharmaceutical-grade nicotine salt along with food-grade ingredients, a type of formulation found in at least some brands made by other manufacturers, according to the company. And whereas the health risk of even food-grade flavors can be brought into question when such flavors are inhaled in smoke or vapor, the consumption of food-grade flavors in nicotine pouches is obviously not open to the same questions.

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    No virgins

    Of course, manufacturers of tobacco/nicotine products can always be accused of adding flavors to attract young people to their products, but a poll by Ipsos Sweden on behalf of Swedish Match seems to indicate that nicotine pouches are adult products, at least in Sweden, to which the poll was confined. According to the results of the poll, 70 percent of nicotine pouch users are between the ages of 26 and 55—or, as a teenager might put it, between old and ancient. Importantly, too, when it comes to gateway issues, the Ipsos poll throws up evidence that nicotine pouches provide a gateway out of traditional tobacco use. While there is a low level of dual cigarette-and-pouch use, there is a high level of previous cigarette use among pouch users. Only 7 percent of nicotine pouch users have never used a nicotine product before taking up pouch use, and most nicotine pouch users consume only pouches while 14 percent use both pouches and snus, and 9 percent use both pouches and cigarettes.

    Dual use often gets bad press, but it can provide an important part in a smoker’s transitioning away from cigarettes or in providing needed relief when she finds herself in a position where she cannot indulge her usual habit. Spokesperson Deborah Perez said that JTI saw its nicotine pouch brand, Nordic Spirit, as responding “to the evolving preferences of adult tobacco and nicotine consumers who are looking for a convenient product that can be used in situations where smoking or vaping is not possible.” And in an email response to TR questions, Imperial Brands, which recently added its nicotine pouch product, ZoneX, to its “asset brands” category, said that it was “assessing opportunities in OND [oral nicotine delivery] as consumers increasingly adopt a multi-category approach to nicotine.”

    To keep up with demand for its Zyn brand, Swedish Match recently expanded its Owensboro, Kentucky, USA, production facility by 16,000 square feet. (Photo: Swedish Match)

    A smaller footprint

    Meanwhile, the Ipsos poll results indicate that 55 percent of pouch users have a university education, and 80 percent are either employed or run their own company. And they also indicated that pouch consumers, who are more likely to live in urban rather than rural areas, consider themselves to be health conscious and believe it is important that the products they buy have only a small impact on the environment.

    Certainly, nicotine pouches seem to be able to lay claim to having a small environmental footprint when compared with other tobacco/nicotine products, and, indeed, some other consumer products. But while their environmental credentials are important, their attraction is also visceral. Perez said that JTI’s pouch brand, Nordic Spirit, provided “a steady, long-lasting nicotine delivery.” Nicotine contents range from 9 mg/g for Nordic Spirit Spearmint Intense to 14 mg/g for Nordic Spirit Elderflower, Nordic Spirit Berry Citrus and Nordic Spirit Smooth Mint and 17mg/g for Nordic Spirit Spearmint Intense Strong.

    In fact, the attraction of nicotine pouches is both visceral and practical. In the U.K. at least, where retail cigarette prices are high, nicotine pouches seem to be well ahead in the price stakes. According to Perez, Nordic Spirit sells there for £6.50 ($8.15) for a pack of 20 whereas, according to U.K. government figures, the average price of a pack of 20 king-size cigarettes is £11.10.

    Given all of the above, it’s not surprising that, just over a year ago in the U.S., Swedish Match went national with Zyn, which it had launched there in 2015; nor that it opened a 16,000-square-foot addition to its production facility in Owensboro, Kentucky, to provide additional capacity to deal with the demand for this brand.

    Perez, meanwhile, was able to report that Nordic Spirit, which was developed in Sweden and launched in 2018, has rapidly grown market share and is now available in Austria, the Czech Republic, Denmark, Sweden, Switzerland and the U.K. “While the tobacco-free nicotine pouches category is still in its infancy, we expect that many adult tobacco and nicotine consumers globally will be interested in trying the product, helping the new category to grow significantly over the coming years,” she said.

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    But perhaps one of the strongest indications that manufacturers have confidence in the nicotine pouch category came with the announcement by Altria in the middle of May that it had submitted “premarket tobacco product applications to the U.S. Food and Drug Administration for 35 On! products on behalf of Helix Innovations, an Altria joint venture responsible for manufacturing and selling On! nicotine pouches globally.”

    “On! products, in seven flavors and five nicotine levels, offer the broadest portfolio of choices in the fast-growing nicotine pouch category for adult tobacco consumers seeking alternatives to traditional tobacco products,” Altria said in its May announcement, which quoted Paige Magness, senior vice president of regulatory affairs for Altria Client Services. “On! nicotine pouches are a key part of our vision to responsibly lead the transition of adult smokers to a noncombustible future,” said Magness. “We believe the supporting science is strong and are committed to working with the agency on these important product submissions.”

    It seems reasonable to assume that no manufacturer, no matter how deep its products, would enter the labyrinthine caves of the FDA’s application processes unless it was confident the products it was submitting for review were almost assured of consumer acceptance and market success—or unless it were accompanied by Theseus, of course.

  • Risk Assessment Determined by Questioning

    Risk Assessment Determined by Questioning

    Photo: 104691896 | © Milkos | Dreamstime.com

    The share of people who believe e-cigarettes are equally harmful or more harmful than traditional cigarettes depends on how the question is asked, according to new research published in Tobacco Control.

    Tobacco companies often claim that a large proportion of the population perceives potential modified risk tobacco products as equally or more harmful than cigarettes, and argue misperceptions need to be corrected using modified risk claims.

    However, the studies they cite predominantly use one specific measurement of comparative risk, according to the researchers.

    Image: Tobacco Control

    The authors studied the way questions were posed in the 2017 Tobacco Products and Risk Perceptions Survey. When asked directly to compare harms of e-cigarettes and cigarettes, 33.9 percent of participants identified e-cigarettes as less harmful than cigarettes, 36.4 percent reported equal harm, 4.3 percent said e-cigarettes were more harmful and 25.3 percent said, “I don’t know.”

    When asked indirectly, however, 42.1 percent identified e-cigarettes as less harmful than cigarettes, 23.8 percent said they were of equal harm, 7.1 percent perceived e-cigarettes to be more harmful and 27.1 percent did not know.

    The authors say researchers should use both direct and indirect risk questions when assessing the public’s perceptions of harms associated with novel tobacco products.

  • Respira to Submit Nebulizer for FDA Approval

    Respira to Submit Nebulizer for FDA Approval

    Photo: Respira Technologies

    Respira Technologies plans to submit an inhaler device to the U.S. Food and Drug Administration by late 2021 for authorization as nicotine-replacement therapy.

    The company aims to disrupt a $618 billion market dominated by decades-old gums and patches from pharmaceutical companies as well as tobacco companies’ electronic nicotine-delivery devices with a nebulizer that converts nicotine to an aerosol.

    Based in West Hollywood, California, USA, Respira Technologies says that the Covid-19 pandemic has sparked new interest in quitting, and today’s users of vapor devices and e-cigarettes need updated cessation products.

    “The reality is we have folks who are addicted to nicotine who never tried combustible products before,” Respira CEO Mario Danek told Bloomberg Technology, referring to tobacco products that are burned like cigarettes and cigars.

    “They’re used to sleeker products, and we have that design.”