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Category: Science & Innovation

  • Study Says Vape Flavors Alter 3K Genes

    Study Says Vape Flavors Alter 3K Genes

    A study published in Frontiers in Oncology found that e-cigarette flavorings were associated with more than 3,000 changes in gene activity among adult vapers, with fruit flavors producing the greatest effects. Researchers analyzed oral cell samples from 35 vapers, 24 smokers, and 24 non-users, finding that fruit-flavored products were linked to changes in 3,124 genes across the genome compared with non-users. The researchers said the findings do not demonstrate that flavored vapes directly cause disease but suggest they may influence biological pathways associated with cancer, cardiovascular, immune, and respiratory conditions.

    The study found fruit flavors accounted for about 31% of the observed gene expression changes, compared with 2.9% for sweet flavors and 0.9% for mint or menthol, while users of multiple flavors exhibited the broadest changes. Researchers also found that more advanced vaping devices were associated with greater changes in gene activity. Despite the findings, the U.K.’s National Health Service continues to state that vaping exposes users to fewer toxins than smoking and remains an effective smoking-cessation aid for adult smokers, while emphasizing that vaping is not risk-free and should not be used by youth or non-smokers.

  • THR Needed for HIV Care, Researcher Says  

    THR Needed for HIV Care, Researcher Says  

    Dr. Jonathan Shuter, an infectious disease physician at Montefiore Einstein and professor of medicine at Albert Einstein College of Medicine in New York, said in an interview with TheBodyPro that smoking-related illnesses now kill more people living with HIV in the United States than the virus itself. He said smoking rates among people with HIV remain around 40% — far higher than in the general population — and that cessation programs have produced disappointing results, with only about one in five smokers successfully quitting.

    Shuter argued that clinicians should adopt a broader harm reduction approach that supports patients who reduce smoking even if they do not quit completely, while emphasizing lung cancer screening, cardiovascular risk management, and tailored interventions that address the different reasons people with HIV smoke. Shuter also said complete switching from cigarettes to vaping could reduce harm compared with smoking, but cautioned that dual use of cigarettes and e-cigarettes offers little health benefit and remains the more common pattern among people living with HIV.

  • Scandit Launches Automated, Age-Verified, Self-Checkout Solution

    Scandit Launches Automated, Age-Verified, Self-Checkout Solution

    Scandit announced the launch of its Age Verified Self-Checkout, a vision AI-powered age verification solution designed to automate purchases of age-restricted products, including tobacco and nicotine products, at self-checkout kiosks. The system enables customers to verify their age in under 10 seconds using a smartphone through facial age estimation or ID scanning, with no additional hardware or app required.

    Scandit said the technology can automatically complete about 80% of age checks, reducing staff intervention, improving compliance, and increasing self-checkout throughput while processing biometric and ID data entirely on the user’s device to meet privacy standards.

  • Tobacco-Free Pouches Are Not Milder Alternative for Mucosa: Study 

    Tobacco-Free Pouches Are Not Milder Alternative for Mucosa: Study 

    A clinical study by Folktandvården Stockholm and the Karolinska Institutet found that tobacco-free nicotine pouches and traditional tobacco-containing snus produce different oral mucosal reactions. While both products were associated with increased tissue thickening as use increased, nicotine pouch users more frequently exhibited inflammatory changes such as erythema and, in some cases, ulceration, making their effects less predictable than those seen with traditional snus.

    The study, which evaluated 272 adults aged 18–30, found no increased risk of cavities or periodontitis in either group over up to six years of use, but researchers said the findings highlight the need for further research into the oral health effects of nicotine pouches and different flavor formulations.

  • Survey Finds 95% Happy Moving from Cigarettes to Pouches

    Survey Finds 95% Happy Moving from Cigarettes to Pouches

    A growing number of UK consumers are turning to nicotine pouches as an alternative to cigarettes and e-cigarettes, according to Haypp’s fourth annual Nicotine Pouch Report. Based on a survey of more than 2,000 nicotine pouch users, the report found that 68% began using pouches to quit smoking, vaping, or both. Forty-three percent said they switched to quit smoking, 40% to quit vaping, and 15% were seeking to stop using both products.

    The survey found that users were primarily drawn to nicotine pouches because they perceived them as healthier (64%), more discreet (64%), and less likely to affect others (52%). Among respondents who switched from cigarettes, 95% reported feeling better after making the change, while 76% reported encouraging others to switch. The products are most commonly used at home (85%) and at work (79%), reflecting their discreet nature.

    Haypp said the findings suggest the UK nicotine market is shifting following the disposable vape ban and the implementation of the Tobacco and Vapes Act, and that the changing regulatory landscape is prompting more adult nicotine users to explore alternatives that do not involve inhalation.

  • Quitting Smoking Motivated Nearly Half of Pouch Users: Study

    Quitting Smoking Motivated Nearly Half of Pouch Users: Study

    Haypp Group, the parent company of Nicokick.com and Northerner.com, released its Nicotine Pouch and Oral Nicotine Report 2026, based on purchasing data from more than 172,000 customers and a survey of 2,245 adult nicotine pouch users. The report found that 46% of respondents said quitting smoking, vaping, or both was a reason they first tried nicotine pouches, while 88% had previously used another nicotine product before adopting pouches. The average age of a first-time online nicotine pouch purchaser was 45, and adults aged 55 to 64 represented the fastest-growing customer segment in 2025.

    The report also highlighted differences between online and physical retail channels. Among surveyed customers, 98% recalled completing age verification when purchasing online, compared with 75% for purchases made in physical stores. Respondents who reported obtaining nicotine pouches while underage most commonly cited local shops (52%), friends (23%), and supermarkets (10%), while only 5% reported obtaining them online. Haypp Group said sales through Nicokick.com and Northerner.com increased 22% in 2025 after adjusting for sales interruptions in certain states and supply constraints affecting leading brands. The company noted that the survey reflects the experiences of its own customers and is not intended to represent the broader U.S. nicotine pouch market.

  • Scientific Review Concludes Vaping ‘Likely’ Causes Cancer

    Scientific Review Concludes Vaping ‘Likely’ Causes Cancer

    A peer-reviewed report published in Carcinogenesis this week concluded that nicotine-based e-cigarettes are “likely” to cause lung and oral cancers, based on a synthesis of more than 100 studies covering animal experiments, chemical analyses, and human biomarker research. It said it has “reached the most unambiguous conclusion to date about the cancer risk posed by e-cigarettes: nicotine-based vapes are likely to cause cancers of the lung and oral cavity.”

    The paper was led by Adjunct Professor Bernard Stewart AM of University of New South Wales, with co-authors from several Australian institutions including the University of Queensland and University of Sydney. Rather than presenting new experimental data, the authors reinterpret existing literature to argue that converging biological and mechanistic evidence is already strong enough to support a causal cancer risk conclusion, even in the absence of long-term population mortality studies.

    However, the findings come from a synthesis paper, meaning conclusions depend heavily on which studies are included and how evidence is weighted, rather than new primary research.

  • PMI-WSJ Study Highlights Human Value in AI-Driven Workplace

    PMI-WSJ Study Highlights Human Value in AI-Driven Workplace

    Philip Morris International and WSJ Intelligence, the in-house thought leadership consultancy for The Wall Street Journal’s commercial sales organization, today (June 23) unveiled preliminary findings from a global study suggesting that uniquely human capabilities will become increasingly valuable as artificial intelligence becomes more deeply embedded in the workplace. Based on a survey of more than 2,500 business professionals across the United States, the United Kingdom, Italy, South Africa, and Brazil, the research found that while AI adoption is accelerating, professionals continue to place greater trust in human judgment for strategic and creative decisions.

    The study found that 83% of respondents use AI for research and information synthesis on a weekly basis, but only 57% report a high level of trust in its outputs. When AI-generated recommendations conflict with human insights, 62% said human intuition should remain the final authority. Respondents identified critical thinking as the most important workplace skill but also the one most at risk of erosion through overreliance on AI, while creative empathy and adaptability were cited as the human capabilities expected to gain the most importance over the next three years.

    The research also highlighted a divide in AI proficiency and trust between senior executives and entry-level employees, with C-suite leaders reporting significantly higher levels of expertise and confidence in AI tools. PMI said the findings support its view that human cognition should be treated as a strategic business resource as companies increasingly integrate AI into their operations, with a full report scheduled for release in September.

  • Study Smoking Rates Impacted by Social Norms

    Study Smoking Rates Impacted by Social Norms

    A new study from the University of California San Diego developed a quantitative tool to measure public attitudes toward smoking restrictions and secondhand smoke exposure across the United States over the past 30 years. Researchers analyzed responses from 1.5 million participants in the Tobacco Use Supplement to the Current Population Survey between 1992 and 2022, creating a “Willingness to Restrict Smoking” (WTRS) scale. The measure captures public support for smoking restrictions in settings such as hospitals, workplaces, restaurants, shopping malls, bars, playgrounds, and casinos.

    The study, led by David Strong and published in BMJ Public Health, found that states with stronger support for smoking restrictions generally had lower smoking rates. Support for smoke-free environments increased steadily over the three-decade period, with hospitals and playgrounds receiving the highest levels of support for smoking bans.

    According to the researchers, the findings provide evidence that tobacco control strategies focused on changing social norms around smoking and secondhand smoke can contribute to declines in smoking prevalence. The WTRS scale is intended to give public health officials and tobacco control programs a new tool to evaluate whether policies and public education campaigns are successfully shifting attitudes toward smoking.

    Source: UC San Diego Today

  • Study: Collective Trauma Reminders Spark Tobacco, Cannabis Cravings

    Study: Collective Trauma Reminders Spark Tobacco, Cannabis Cravings

    New research from the Hebrew University of Jerusalem and the Israel Center for Addiction and Mental Health finds that merely being reminded of a collective trauma can trigger an immediate, measurable spike in cravings for tobacco and cannabis among regular users. The study, led by Dr. Vera Skvirsky and Dr. Uri Lifshin with colleagues, frames these sudden cravings as a reflexive psychological defense rooted in existential fear, a rapid mental shield against thoughts of mortality and vulnerability. It draws on terror management theory, which holds that humans, uniquely aware of their own mortality, instinctively deploy defenses against existential threats; the researchers suggest the urge to smoke functions as one such rapid “proximal defense.”

    The team ran two experiments. In the first, moderate-to-high-risk cannabis users read an article recounting the October 7 attack on Israel with recognizable images, while a control group read about dental pain; those exposed to the trauma reminder reported significantly heightened cannabis craving. The second experiment replicated the design with daily tobacco smokers and produced the same surge in nicotine cravings. Lifshin said the findings show how addictive behaviors are intertwined with a basic need for psychological survival, with the urge to smoke acting as a defensive response that pushes thoughts of mortality out of awareness.

    The data also showed that individuals with high attachment anxiety reported higher overall cravings. Notably, traditional anxiety buffers — attachment security, self-esteem, strong national identity, and self-affirmation tasks — did not diminish the cravings triggered by trauma reminders, suggesting the impulse is an urgent reflex to suppress threatening thoughts rather than a strategy to build psychological security. The authors argue that as societies grapple with war, terrorism, displacement, and uncertainty, understanding how existential fear shapes addictive behavior becomes more important, and they note that trauma reminders in news media may influence health-related behaviors even after the event itself has passed. The study appears in the Journal of Health Psychology.