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Tag: cbd

  • CBD Could Help Stop Smoking

    CBD Could Help Stop Smoking

    Photo: EKKAPON

    Cannabidiol (CBD) could help tobacco users quit, according to a new study published in Chemical Research in Toxicology.

    Washington State University researchers tested effects of CBD and its major metabolite on human liver tissue and cell samples and found that it inhibited a key enzyme for nicotine metabolism. Slowing nicotine metabolism could allow users to wait longer before feeling the need for more. More research is needed, but according to Philip Lazarus, Washington State University professor of pharmaceutical sciences, the findings are promising.

    “The whole mission is to decrease harm from smoking, which is not from the nicotine per se but all the carcinogens and other chemicals that are in tobacco smoke,” said Lazarus, senior author on the study. “If we can minimize that harm, it would be a great thing for human health.”

    “It appears that you don’t need much CBD to see the effect,” said Lazarus.

    Lazarus’ team is developing a clinical study to examine the effects of CBD on nicotine levels in smokers, measuring nicotine levels in their blood versus smokers taking a placebo over the course of six hours to eight hours. They hope to then do a much larger study looking at CBD and nicotine addiction.

  • U.S. FDA May Publish Draft Guidance for CBD

    U.S. FDA May Publish Draft Guidance for CBD

    The U.S. Food and Drug Administration is planning to make recommendations on how to regulate the use of the popular cannabis compound cannabidiol (CBD) in food and supplements, the Wall Street Journal reported, citing agency officials.

    After weighing the evidence on the compound’s safety, the FDA will decide within months how to regulate legal cannabis and whether that will require new agency rules or new legislation from Congress, according to the report.

    In an interview, Janet Woodcock, the FDA’s deputy commissioner and leader of the agency’s cannabis regulation efforts, expressed concern about the safety of CBD and whether current regulatory pathways for food and dietary supplements are suitable for this substance.

    However, the agency is interested in determining whether it is safe to consume CBD on a daily basis for extended periods of time or during pregnancy.

    Woodcock mentioned concerns about potential effects on fertility in the future, but, at the same time, her comment signaled that the agency is working to establish regulatory frameworks for the legal sale of appropriate cannabis and cannabis-derived products.

    CBD is a chemical compound found in cannabis plants. It is one of the main ingredients in cannabis, but unlike THC, it does not cause a high or have psychoactive effects.

    The 2018 Farm Bill legalized hemp cultivation in the U.S., which led to significant growth in the market for CBD products. These products, sold as dietary supplements, are believed to have health benefits. As a result, many businesses in the cannabis industry are now selling CBD products across the country.

    Over the last few years, the FDA posted several warning letters to companies for illegally selling products containing CBD. The companies are accused of selling products containing CBD that the FDA states some people may confuse for traditional foods or beverages that do not contain CBD or were making medical claims about their CBD products.

    In 2021, The FDA told Charlotte’s Web Holdings, one of the world’s largest CBD companies, that its cannabidiol product cannot be sold as a dietary supplement, signaling that CBD reform may have to wait for congressional action.