Tag: cbd

  • CBD Could Help Stop Smoking

    CBD Could Help Stop Smoking

    Photo: EKKAPON

    Cannabidiol (CBD) could help tobacco users quit, according to a new study published in Chemical Research in Toxicology.

    Washington State University researchers tested effects of CBD and its major metabolite on human liver tissue and cell samples and found that it inhibited a key enzyme for nicotine metabolism. Slowing nicotine metabolism could allow users to wait longer before feeling the need for more. More research is needed, but according to Philip Lazarus, Washington State University professor of pharmaceutical sciences, the findings are promising.

    “The whole mission is to decrease harm from smoking, which is not from the nicotine per se but all the carcinogens and other chemicals that are in tobacco smoke,” said Lazarus, senior author on the study. “If we can minimize that harm, it would be a great thing for human health.”

    “It appears that you don’t need much CBD to see the effect,” said Lazarus.

    Lazarus’ team is developing a clinical study to examine the effects of CBD on nicotine levels in smokers, measuring nicotine levels in their blood versus smokers taking a placebo over the course of six hours to eight hours. They hope to then do a much larger study looking at CBD and nicotine addiction.

  • U.S. FDA May Publish Draft Guidance for CBD

    U.S. FDA May Publish Draft Guidance for CBD

    The U.S. Food and Drug Administration is planning to make recommendations on how to regulate the use of the popular cannabis compound cannabidiol (CBD) in food and supplements, the Wall Street Journal reported, citing agency officials.

    After weighing the evidence on the compound’s safety, the FDA will decide within months how to regulate legal cannabis and whether that will require new agency rules or new legislation from Congress, according to the report.

    In an interview, Janet Woodcock, the FDA’s deputy commissioner and leader of the agency’s cannabis regulation efforts, expressed concern about the safety of CBD and whether current regulatory pathways for food and dietary supplements are suitable for this substance.

    However, the agency is interested in determining whether it is safe to consume CBD on a daily basis for extended periods of time or during pregnancy.

    Woodcock mentioned concerns about potential effects on fertility in the future, but, at the same time, her comment signaled that the agency is working to establish regulatory frameworks for the legal sale of appropriate cannabis and cannabis-derived products.

    CBD is a chemical compound found in cannabis plants. It is one of the main ingredients in cannabis, but unlike THC, it does not cause a high or have psychoactive effects.

    The 2018 Farm Bill legalized hemp cultivation in the U.S., which led to significant growth in the market for CBD products. These products, sold as dietary supplements, are believed to have health benefits. As a result, many businesses in the cannabis industry are now selling CBD products across the country.

    Over the last few years, the FDA posted several warning letters to companies for illegally selling products containing CBD. The companies are accused of selling products containing CBD that the FDA states some people may confuse for traditional foods or beverages that do not contain CBD or were making medical claims about their CBD products.

    In 2021, The FDA told Charlotte’s Web Holdings, one of the world’s largest CBD companies, that its cannabidiol product cannot be sold as a dietary supplement, signaling that CBD reform may have to wait for congressional action.

  • BAT Launches CBD Vapor Product

    BAT Launches CBD Vapor Product

    British American Tobacco (BAT) has pilot-launched its first CBD vaping product, Vuse CBD Zone.

    This new range is available in three e-liquid flavors—mint, mango, and berry—and two strengths—50 mg and 100 mg. Vuse CBD Zone is initially being launched Manchester, U.K., in convenience stores and online (online purchase is geofenced for Manchester residents). Further rollout plans are anticipated for later in the year.

    “With the rollout of Vuse CBD Zone in Manchester, our unique multicategory portfolio now, for the first time, offers products that go beyond nicotine,” said Fredrik Svensson, general manager at BAT U.K. and Ireland, in a statement. “CBD vaping is a new category for us, and we will be using this pilot launch to gain key learnings about consumer and retailer experiences, combined with our extensive expertise and knowledge of vaping, to help inform plans for a potential nationwide roll-out of Vuse CBD Zone later in the year.”

  • Vilosophy Launches Oils and Pouches

    Vilosophy Launches Oils and Pouches

    Photo: Vilosophy

    Vilosophy has launched V&YOU, a portfolio of premium products with “active” ingredients, in the United Kingdom.

    V&YOU products are available in four “vibes”—calm, chill, focus and boost. They include CBD oils and pouches, as well as nicotine pouches. According to Vilosophy, the V&YOU CBD and nicotine pouches provide a new, discreet and convenient way to consume either ingredient.

    V&YOU products adhere to the strictest quality standards and are sold an accessible price, according to the manufacturer.

    “We are excited that our first brand V&YOU will be one of the only producers of nicotine pouches in the U.K.,” says Vilosophy CEO Wouda Kuipers, who founded the company with Ged Shudall and Markus Bonke, two seasoned executives from the fast-moving consumer goods space.

    “Pouches are incredibly popular across Europe and we think people in the U.K. will find them a convenient way to take nicotine; they also provide longer lasting flavors,” adds Wouda Kuipers.

    “Vilosophy has been founded on the belief that people should be free to choose how they live their life and our aim is to develop a portfolio of lifestyle brands that bring premium active ingredients to market, in a way that is best for people,” he says.  

     

  • Criticality opens hemp plant

    Criticality opens hemp plant

    The U.S. market for cannabidiol (CBD) oil is about to explode, and Criticality, an integrated industrial hemp company, is in a prime position to serve it. On March 12, the company inaugurated a 55,000-square-foot, state-of-the-art extraction and purification facility in Wilson, North Carolina, USA. In a ceremony attended by employees, business partners and press representatives, senior management and local dignitaries cut a ribbon and wrote a new chapter in Criticality’s remarkable history.

    Derived from hemp plant, CBD can be used to treat a variety of health issues, including anxiety, insomnia and chronic pain. According to Harvard Medical School, it has also been proven to be effective in treating childhood epilepsy syndromes that typically don’t respond to antiseizure medications.

    Like marijuana, hemp is a species of cannabis. Both species contain tetrahydrocannabinol, a potentially psychoactive constituent. However, the levels in hemp are so low—less than 0.3 percent—that products derived from hemp do not intoxicate the user.

    In recent years, CBD sales have skyrocketed. In the U.S. alone, CBD consumption increased from $108.1 million to $512.7 million between 2014 and 2018, according to the Hemp Business Journal. This year, the publication forecasts sales of $813.2 million. But the real growth has yet to come. Analysts of the Brightfield Group expect the U.S. CBD market to hit a whopping $22 billion by 2022.

    Much of that growth is related to the legalization of industrial hemp and related products. The 2014 U.S. Agricultural Act permitted select research and state departments to grow industrial hemp as part of agricultural pilot programs. Criticality joined North Carolina’s program, following the state’s legalization of medical marijuana in 2014.

    In 2017, Pyxus International, the parent company of leaf tobacco merchant Alliance One International, purchased a 40 percent share in Criticality. Faced with declining demand for tobacco, Pyxus has been exploring new business opportunities where it can leverage its expertise in agronomy and agricultural supply chains, along with its extensive farmer base.

    According to specialists, there are many similarities between the cultivation of tobacco and that of hemp. Tobacco transplanting equipment and curing barns, for example, can easily be adapted for hemp production. And now, the potential offered by CBD has been turbocharged by the 2018 U.S. Farm Bill, which became law in December and legalized the cultivation of industrial hemp nationwide, removing it from the Controlled Substances Act.

    “Through our investment in Criticality […] our goal is to become a leader in the production of CBD and related consumer products,” said Pyxus President, CEO and Chairman Pieter Sikkel. “The opening of the facility is a critical step in achieving that goal and is a glimpse of what’s to come in the future.”

    Unsurprisingly, many companies have entered the hemp business, hoping to cash in on the growing popularity of CBD. Criticality intends to set itself apart through meticulous attention to quality and compliance—both with current and future regulations. During the Wilson ceremony, Criticality CEO Brian Moyer said the company is committed to producing a fully traceable product, using good manufacturing practices and meeting all applicable dietary supplement guidelines.

    Criticality’s Chief Technical Officer Jose Martinez compares the company’s CBD extraction process from hemp to the process used by coffee manufacturers to remove caffeine from beans. But rather than using environmentally harmful solvents, he says, Criticality relies on carbon dioxide, one of the most common elements in nature. While carbon dioxide is also a greenhouse gas, Martinez is quick to point out that the extraction process does not generate carbon dioxide; the gas used already exists.

    Wilson Mayor C. Bruce Rose and Wilson Chamber of Commerce President Ryan Simons praised not only Criticality’s innovative spirit but also the company’s contribution to the local economy.

    The factory is expected to generate 88 relatively high-paying jobs by 2024—a figure that might increase even further if the hemp market continues its current growth trajectory.

    Anticipating strong demand, Moyer noted that the facility has been designed with expansion in mind. “This factory is only the beginning,” he said.