A growing body of research suggests that nicotine patches and gum, traditionally used to help people quit smoking, may offer off-label benefits for treating various cognitive issues like ADHD, Alzheimer’s, brain fog, schizophrenia, depression, and Parkinson’s disease. Doctors like Edward Levin (Duke University) and Paul Newhouse (Vanderbilt) have found that nicotine can stimulate brain receptors tied to attention and memory.
One 2023 study reported that nicotine patches improved concentration in long COVID brain fog sufferers, sparking interest from users like Slate writer Hannah Singleton, who found that low-dose nicotine gum dramatically improved her focus.
Unlike tobacco products, nicotine patches deliver the substance in controlled, low-risk doses, making them potentially safe for non-smokers. However, experts caution that this remains experimental, with no FDA-approved protocols yet. Still, amid ongoing stimulant shortages, nicotine’s role as a cognitive aid is gaining attention.